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Flight Deals from Detroit to Charlotte from $105

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Bundle + Save

Top flight deals from leading airlines:

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

Nonstop
from $210
Up to 1 stop
$189

Airlines

American Airlines
$242
Delta Air Lines
$242
Frontier Airlines
$199
Southwest Airlines
$307
Spirit Airlines
$189
United Airlines
$332

Cabin Class

Economy
$189

Departure Airports

Detroit Metropolitan Airport
$189

Arrival Airports

Charlotte Douglas International Airport
$189

Layover Airports

Baltimore/Washington International Thurgood Marshall Airport
$307
Chicago O Hare Airport
$242
Dallas Fort Worth International Airport
$353
Fort Lauderdale Hollywood International Airport
$189
Hartsfield Jackson Atlanta International Airport
$252
New York LaGuardia Airport
$189
Newark Liberty Airport
$251
Orlando International Airport
$199
Philadelphia International Airport
$347
Reagan Washington National Airport
$322
St Louis Lambert International Airport
$307
Washington Dulles Airport
$332

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
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BUNDLE & SAVE

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On average save $240 per traveler
Spirit Airlines Logo
Spirit Airlines

05/02/25

2:59pm
DTW
9h 28m
FLL

05/03/25

12:27am
CLT
Spirit Airlines Logo
Spirit Airlines

05/05/25

8:35pm
CLT
11h 45m
LGA

05/06/25

8:20am
DTW
$189
Free cancellation within 83 hours of booking
Spirit Airlines Logo
Spirit Airlines

05/11/25

8:18pm
DTW
14h 10m
LGA

05/12/25

10:28am
CLT
Spirit Airlines Logo
Spirit Airlines

05/18/25

5:52pm
CLT
1h 43m
Direct

05/18/25

7:35pm
DTW
$191
Free cancellation within 83 hours of booking
Frontier Airlines Logo
Frontier Airlines

05/02/25

9:58pm
DTW
19h 54m
MCO

05/03/25

5:52pm
CLT
Frontier Airlines Logo
Frontier Airlines

05/05/25

9:47am
CLT
8h 13m
MCO

05/05/25

6:00pm
DTW
$199
Free cancellation within 83 hours of booking
Spirit Airlines Logo
Spirit Airlines

05/22/25

8:55am
DTW
1h 52m
Direct

05/22/25

10:47am
CLT
Spirit Airlines Logo
Spirit Airlines

05/29/25

5:52pm
CLT
1h 43m
Direct

05/29/25

7:35pm
DTW
$210
Free cancellation within 83 hours of booking
Spirit Airlines Logo
Spirit Airlines

05/12/25

8:55am
DTW
1h 52m
Direct

05/12/25

10:47am
CLT
Spirit Airlines Logo
Spirit Airlines

05/19/25

5:52pm
CLT
1h 43m
Direct

05/19/25

7:35pm
DTW
$210
Free cancellation within 83 hours of booking
Spirit Airlines Logo
Spirit Airlines

05/16/25

8:55am
DTW
1h 52m
Direct

05/16/25

10:47am
CLT
Spirit Airlines Logo
Spirit Airlines

05/23/25

5:52pm
CLT
1h 43m
Direct

05/23/25

7:35pm
DTW
$210
Free cancellation within 83 hours of booking
Delta Air Lines Logo
Delta Air Lines

05/24/25

5:45pm
DTW
1h 46m
Direct

05/24/25

7:31pm
CLT
Delta Air Lines Logo
Delta Air Lines

05/31/25

1:19pm
CLT
1h 48m
Direct

05/31/25

3:07pm
DTW
$242
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/05/25

5:30am
DTW
9h 39m
ORD

05/05/25

3:09pm
CLT
American Airlines Logo
American Airlines

05/05/25

6:47pm
CLT
1h 47m
Direct

05/05/25

8:34pm
DTW
$242
Free cancellation within 83 hours of booking
Spirit Airlines Logo
Spirit Airlines

05/22/25

8:55am
DTW
1h 52m
Direct

05/22/25

10:47am
CLT
Spirit Airlines Logo
Spirit Airlines

05/29/25

11:52am
CLT
7h 57m
EWR

05/29/25

7:49pm
DTW
$251
Free cancellation within 83 hours of booking
Delta Air Lines Logo
Delta Air Lines

05/24/25

10:25am
DTW
1h 46m
Direct

05/24/25

12:11pm
CLT
Delta Air Lines Logo
Delta Air Lines

05/31/25

7:00am
CLT
5h 55m
ATL

05/31/25

12:55pm
DTW
$252
Free cancellation within 83 hours of booking
Delta Air Lines Logo
Delta Air Lines

05/11/25

2:05pm
DTW
1h 48m
Direct

05/11/25

3:53pm
CLT
Delta Air Lines Logo
Delta Air Lines

05/17/25

5:14pm
CLT
1h 50m
Direct

05/17/25

7:04pm
DTW
$257
Free cancellation within 83 hours of booking
Delta Air Lines Logo
Delta Air Lines

05/24/25

7:45pm
DTW
4h 7m
ATL

05/24/25

11:52pm
CLT
Delta Air Lines Logo
Delta Air Lines

05/31/25

8:20am
CLT
4h 35m
ATL

05/31/25

12:55pm
DTW
$262
Free cancellation within 83 hours of booking
Southwest Airlines Logo
Southwest Airlines

05/02/25

12:40pm
DTW
5h 25m
STL

05/02/25

6:05pm
CLT
Southwest Airlines Logo
Southwest Airlines

05/05/25

7:30am
CLT
4h 50m
BWI

05/05/25

12:20pm
DTW
$307
Free cancellation within 83 hours of booking
Spirit Airlines Logo
Spirit Airlines

05/16/25

8:55am
DTW
1h 52m
Direct

05/16/25

10:47am
CLT
Spirit Airlines Logo
Spirit Airlines

05/23/25

11:52am
CLT
7h 57m
EWR

05/23/25

7:49pm
DTW
$307
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/24/25

5:16pm
DTW
1h 54m
Direct

05/24/25

7:10pm
CLT
American Airlines Logo
American Airlines

05/31/25

2:41pm
CLT
1h 45m
Direct

05/31/25

4:26pm
DTW
$312
Free cancellation within 83 hours of booking
Spirit Airlines Logo
Spirit Airlines

05/02/25

2:59pm
DTW
9h 28m
FLL

05/03/25

12:27am
CLT
Spirit Airlines Logo
Spirit Airlines

05/05/25

8:41am
CLT
5h 10m
EWR

05/05/25

1:51pm
DTW
$318
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/24/25

3:35pm
DTW
1h 55m
Direct

05/24/25

5:30pm
CLT
American Airlines Logo
American Airlines

05/31/25

4:41pm
CLT
5h 24m
DCA

05/31/25

10:05pm
DTW
$322
Free cancellation within 83 hours of booking
Delta Air Lines Logo
Delta Air Lines

05/02/25

9:30pm
DTW
1h 44m
Direct

05/02/25

11:14pm
CLT
Delta Air Lines Logo
Delta Air Lines

05/05/25

4:29pm
CLT
6h 29m
LGA

05/05/25

10:58pm
DTW
$331
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/24/25

5:30am
DTW
4h 35m
ORD

05/24/25

10:05am
CLT
American Airlines Logo
American Airlines

05/31/25

1:00pm
CLT
4h 18m
ORD

05/31/25

5:18pm
DTW
$332
Free cancellation within 83 hours of booking
United Airlines Logo
United Airlines

05/06/25

10:15am
DTW
3h 56m
IAD

05/06/25

2:11pm
CLT
United Airlines Logo
United Airlines

05/13/25

10:41am
CLT
4h 39m
ORD

05/13/25

3:20pm
DTW
$332
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/11/25

3:35pm
DTW
1h 55m
Direct

05/11/25

5:30pm
CLT
American Airlines Logo
American Airlines

05/17/25

4:41pm
CLT
5h 24m
DCA

05/17/25

10:05pm
DTW
$337
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/11/25

7:30am
DTW
4h 51m
PHL

05/11/25

12:21pm
CLT
American Airlines Logo
American Airlines

05/17/25

6:22pm
CLT
6h 7m
ORD

05/18/25

12:29am
DTW
$347
Free cancellation within 83 hours of booking
United Airlines Logo
United Airlines

05/11/25

2:05pm
DTW
7h 16m
ORD

05/11/25

9:21pm
CLT
United Airlines Logo
United Airlines

05/17/25

5:30pm
CLT
4h 37m
ORD

05/17/25

10:07pm
DTW
$347
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/23/25

10:15am
DTW
2h
Direct

05/23/25

12:15pm
CLT
American Airlines Logo
American Airlines

05/25/25

8:10am
CLT
4h 11m
PHL

05/25/25

12:21pm
DTW
$352
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/22/25

7:30am
DTW
6h 10m
PHL

05/22/25

1:40pm
CLT
American Airlines Logo
American Airlines

05/29/25

9:25am
CLT
1h 52m
Direct

05/29/25

11:17am
DTW
$352
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/06/25

5:43pm
DTW
6h 42m
DFW

05/07/25

12:25am
CLT
American Airlines Logo
American Airlines

05/13/25

5:15pm
CLT
7h 37m
DFW

05/14/25

12:52am
DTW
$353
Free cancellation within 83 hours of booking
United Airlines Logo
United Airlines

05/23/25

4:17pm
DTW
5h 13m
ORD

05/23/25

9:30pm
CLT
United Airlines Logo
United Airlines

05/25/25

7:42pm
CLT
4h 14m
IAD

05/25/25

11:56pm
DTW
$362
Free cancellation within 83 hours of booking
American Airlines Logo
American Airlines

05/22/25

5:25pm
DTW
6h 30m
DCA

05/22/25

11:55pm
CLT
American Airlines Logo
American Airlines

05/29/25

9:44am
CLT
5h 37m
PHL

05/29/25

3:21pm
DTW
$362
Free cancellation within 83 hours of booking
United Airlines Logo
United Airlines

05/26/25

2:10pm
DTW
7h 20m
ORD

05/26/25

9:30pm
CLT
United Airlines Logo
United Airlines

06/01/25

6:30am
CLT
6h 52m
ORD

06/01/25

1:22pm
DTW
$362
Free cancellation within 83 hours of booking
United Airlines Logo
United Airlines

05/09/25

2:05pm
DTW
7h 16m
ORD

05/09/25

9:21pm
CLT
United Airlines Logo
United Airlines

05/14/25

7:40pm
CLT
4h 19m
IAD

05/14/25

11:59pm
DTW
$375
Free cancellation within 83 hours of booking

Top Deals on flights from Detroit to Charlotte

Detroit, US (DTT) - Charlotte, US (CLT)

Spirit Airlines Logo
Spirit Airlines

May 12

8:55am
DTW
1h 52m
Direct

May 12

10:47am
CLT

as low as

$105

Detroit, US (DTT) - Charlotte, US (CLT)

Spirit Airlines Logo
Spirit Airlines

May 2

2:59pm
DTW
9h 28m
FLL

May 3

12:27am
CLT

as low as

$114

Detroit, US (DTT) - Charlotte, US (CLT)

Frontier Airlines Logo
Frontier Airlines

May 2

9:58pm
DTW
19h 54m
MCO

May 3

5:52pm
CLT

as low as

$120

Detroit, US (DTT) - Charlotte, US (CLT)

Southwest Airlines Logo
Southwest Airlines

May 2

12:40pm
DTW
5h 25m
STL

May 2

6:05pm
CLT

as low as

$161

Detroit, US (DTT) - Charlotte, US (CLT)

American Airlines Logo
American Airlines

May 2

5:21pm
DTW
1h 53m
Direct

May 2

7:14pm
CLT

as low as

$228

Detroit, US (DTT) - Charlotte, US (CLT)

Delta Air Lines Logo
Delta Air Lines

May 8

7:10am
DTW
1h 43m
Direct

May 8

8:53am
CLT

as low as

$228

Detroit, US (DTT) - Charlotte, US (CLT)

American Airlines Logo
American Airlines

May 2

5:25am
DTW
4h 39m
ORD

May 2

10:04am
CLT

as low as

$238

Detroit, US (DTT) - Charlotte, US (CLT)

Delta Air Lines Logo
Delta Air Lines

Apr 29

12:15pm
DTW
4h 11m
ATL

Apr 29

4:26pm
CLT

as low as

$238

Detroit, US (DTT) - Charlotte, US (CLT)

United Airlines Logo
United Airlines

May 21

9:20am
DTW
8h 16m
ORD

May 21

5:36pm
CLT

as low as

$257

Detroit, US (DTT) - Charlotte, US (CLT)

American Airlines Logo
American Airlines

May 24

11:34am
DTW
7h 33m
DCA

May 24

7:07pm
CLT

as low as

$264

Detroit, US (DTT) - Charlotte, US (CLT)

United Airlines Logo
United Airlines

May 6

11:02am
DTW
10h 57m
IAH

May 6

9:59pm
CLT

as low as

$269

Detroit, US (DTT) - Charlotte, US (CLT)

United Airlines Logo
United Airlines

May 2

7:44pm
DTW
4h 14m
IAD

May 2

11:58pm
CLT

as low as

$273
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