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Flight Deals from Denver to Mayagueez from $352

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Bundle + Save

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Incredible Deals

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 1 stop
    $1099
  • Up to 2 stops
    $731

Airlines

  • JetBlue
    $731
  • United Airlines
    $953

Cabin Class

  • Economy
    $731

Departure Airports

  • Denver International Airport
    $731

Arrival Airports

  • Eugenio Maria De Hostos Airport
    $731

Layover Airports

  • Chicago O Hare Airport
    $1025
  • General Edward Lawrence Logan International Airport
    $786
  • George Bush Intercontinental Houston Airport
    $958
  • Luis Munoz Marin International Airport
    $731
  • New York John F Kennedy Airport
    $731
  • Newark Liberty Airport
    $953
  • Washington Dulles Airport
    $1025

Best Price. GUARANTEED.

Exclusively for Priceline Members
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We'll refund the difference if you find a lower price.

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BUNDLE & SAVE
Book a flight & hotel together for extra savings.
On average save $240 per traveler
JetBlue Logo
JetBlue

08/01/25

DEN
27h 2m
JFK
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
17h 24m
SJU
JFK

08/08/25

DEN
$731
JetBlue Logo
JetBlue

08/01/25

DEN
19h 49m
JFK
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
15h 23m
SJU
JFK

08/08/25

DEN
$731
JetBlue Logo
JetBlue

08/01/25

DEN
19h 49m
JFK
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
17h 24m
SJU
JFK

08/08/25

DEN
$731
JetBlue Logo
JetBlue

08/01/25

DEN
27h 2m
JFK
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
15h 23m
SJU
JFK

08/08/25

DEN
$731
JetBlue Logo
JetBlue

08/01/25

DEN
18h 3m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
17h 24m
SJU
JFK

08/08/25

DEN
$786
JetBlue Logo
JetBlue

08/01/25

DEN
18h 3m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
15h 23m
SJU
JFK

08/08/25

DEN
$786
JetBlue Logo
JetBlue

08/01/25

DEN
15h 48m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
17h 24m
SJU
JFK

08/08/25

DEN
$816
JetBlue Logo
JetBlue

08/01/25

DEN
15h 48m
BOS
SJU

08/02/25

MAZ
JetBlue Logo
JetBlue

08/08/25

MAZ
15h 23m
SJU
JFK

08/08/25

DEN
$816
United Airlines Logo
United Airlines

08/01/25

DEN
14h 33m
EWR
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
12h 36m
SJU

08/08/25

DEN
$953
United Airlines Logo
United Airlines

08/01/25

DEN
14h 33m
EWR
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
10h 35m
SJU

08/08/25

DEN
$953
United Airlines Logo
United Airlines

08/01/25

DEN
21h 22m
IAH
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
10h 35m
SJU

08/08/25

DEN
$958
United Airlines Logo
United Airlines

08/01/25

DEN
21h 22m
IAH
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
12h 36m
SJU

08/08/25

DEN
$958
United Airlines Logo
United Airlines

08/01/25

DEN
21h 22m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
12h 30m
SJU
IAD

08/09/25

DEN
$1025
United Airlines Logo
United Airlines

08/01/25

DEN
21h 22m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
11h 22m
SJU
ORD

08/08/25

DEN
$1025
United Airlines Logo
United Airlines

08/01/25

DEN
14h 28m
IAD
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
10h 35m
SJU

08/08/25

DEN
$1073
United Airlines Logo
United Airlines

08/01/25

DEN
14h 28m
IAD
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
12h 36m
SJU

08/08/25

DEN
$1073
United Airlines Logo
United Airlines

08/01/25

DEN
28h 44m
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
10h 35m
SJU

08/08/25

DEN
$1099
United Airlines Logo
United Airlines

08/01/25

DEN
28h 44m
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
12h 36m
SJU

08/08/25

DEN
$1099
United Airlines Logo
United Airlines

08/01/25

DEN
14h 33m
EWR
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
11h 22m
SJU
ORD

08/08/25

DEN
$1100
United Airlines Logo
United Airlines

08/01/25

DEN
14h 33m
EWR
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
12h 30m
SJU
IAD

08/09/25

DEN
$1100
United Airlines Logo
United Airlines

08/01/25

DEN
17h 32m
ORD
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
12h 36m
SJU

08/08/25

DEN
$1103
United Airlines Logo
United Airlines

08/01/25

DEN
20h 42m
IAH
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
12h 36m
SJU

08/08/25

DEN
$1103
United Airlines Logo
United Airlines

08/01/25

DEN
17h 32m
ORD
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
10h 35m
SJU

08/08/25

DEN
$1103
United Airlines Logo
United Airlines

08/01/25

DEN
19h 22m
IAH
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
10h 35m
SJU

08/08/25

DEN
$1103
United Airlines Logo
United Airlines

08/01/25

DEN
19h 22m
IAH
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
12h 36m
SJU

08/08/25

DEN
$1103
United Airlines Logo
United Airlines

08/01/25

DEN
20h 42m
IAH
SJU

08/02/25

MAZ
Cape Air Logo
Cape Air

08/08/25

MAZ
10h 35m
SJU

08/08/25

DEN
$1103
United Airlines Logo
United Airlines

08/01/25

DEN
14h 33m
EWR
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
18h 43m
SJU
ORD

08/09/25

DEN
$1120
United Airlines Logo
United Airlines

08/01/25

DEN
21h 22m
IAH
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
18h 43m
SJU
ORD

08/09/25

DEN
$1125
United Airlines Logo
United Airlines

08/01/25

DEN
17h 32m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
11h 22m
SJU
ORD

08/08/25

DEN
$1131
United Airlines Logo
United Airlines

08/01/25

DEN
17h 32m
ORD
SJU

08/02/25

MAZ
United Airlines Logo
United Airlines

08/08/25

MAZ
12h 30m
SJU
IAD

08/09/25

DEN
$1131

Top Deals on flights from Denver to Mayagueez

Denver, US (DEN) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

DEN
19h 49m
JFK
SJU

Aug 2

MAZ

as low as

$352

Denver, US (DEN) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

DEN
27h 2m
JFK
SJU

Aug 2

MAZ

as low as

$358

Denver, US (DEN) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

DEN
24h 2m
JFK
SJU

Aug 2

MAZ

as low as

$372

Denver, US (DEN) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

DEN
18h 3m
BOS
SJU

Aug 2

MAZ

as low as

$423

Denver, US (DEN) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

DEN
15h 48m
BOS
SJU

Aug 2

MAZ

as low as

$453

Denver, US (DEN) - Mayagueez, PR (MAZ)

JetBlue Logo
JetBlue

Aug 1

DEN
12h 48m
BOS
SJU

Aug 2

MAZ

as low as

$473

Denver, US (DEN) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

DEN
21h 22m
IAH
SJU

Aug 2

MAZ

as low as

$527

Denver, US (DEN) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

DEN
20h 42m
IAH
SJU

Aug 2

MAZ

as low as

$712

Denver, US (DEN) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

DEN
19h 22m
IAH
SJU

Aug 2

MAZ

as low as

$712

Denver, US (DEN) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

DEN
28h 44m
SJU

Aug 2

MAZ

as low as

$718

Denver, US (DEN) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

DEN
25h 2m
ORD
SJU

Aug 2

MAZ

as low as

$798

Denver, US (DEN) - Mayagueez, PR (MAZ)

United Airlines Logo
United Airlines

Aug 1

DEN
25h 52m
EWR
SJU

Aug 2

MAZ

as low as

$798

Frequently Asked Questions

What are the most convenient layover airports for my flight?
Consider layovers at New York John F Kennedy Airport, Luis Munoz Marin International Airport, Newark Liberty Airport, General Edward Lawrence Logan International Airport, and Luis Munoz Marin International Airport for your journey.
What is the cheapest and fastest flight from Denver to Mayagueez?
The cheapest flight is with JetBlue at $731, taking 19 hours 49 minutes. The fastest flight, also with JetBlue, costs $836 and takes 12 hours 48 minutes.
What are all possible destination arrival airports?
The possible destination arrival airport for your flight is Eugenio Maria De Hostos Airport in Mayagueez, Puerto Rico.
What is the time difference between destination and arrival?
You will arrive in Mayagueez approximately 2 hours ahead of Denver due to the time zone difference. Please check your flight details for exact arrival times.
Is there a direct flight from Denver to Mayagueez?
There is no direct flight from Denver to Mayagueez. The available options include 1-stop and 2-stop flights with airlines such as JetBlue at $731 and United Airlines at $953. The flight durations range from 12 hours 48 minutes to 28 hours 44 minutes.
Are there convenient layover flights from Denver to Mayagueez?
Yes, convenient flights include a 2 stops flight with JetBlue for $731 and United Airlines for $953. Additionally, a 1 stop flight is available with United Airlines for $1099.
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