$227 Flight Deals from Buffalo to Medellin

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Stops

Up to 1 stop
$900
Up to 2 stops
$563

Airlines

American Airlines
$631
JetBlue
$563
LATAM Airlines Group
$956

Cabin Class

Economy
$563

Departure Airports

Buffalo Niagara International Airport
$563

Arrival Airports

Jose Maria Córdova International Airport
$563

Layover Airports

Charlotte Douglas International Airport
$631
Chicago O Hare Airport
$713
El Dorado International Airport
$956
Fort Lauderdale Hollywood International Airport
$563
Hartsfield Jackson Atlanta International Airport
$956
Luis Munoz Marin International Airport
$563
Miami International Airport
$631
New York John F Kennedy Airport
$563

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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

JetBlue

11/14/25

6:32pm

BUF

18h 30m

JFK

SJU

11/15/25

1:02pm

MDE

JetBlue

11/22/25

2:25pm

MDE

26h 41m

FLL

11/23/25

5:06pm

BUF

^$563

JetBlue

11/14/25

6:32pm

BUF

18h 30m

JFK

SJU

11/15/25

1:02pm

MDE

JetBlue

11/22/25

2:25pm

MDE

19h

FLL

JFK

11/23/25

9:25am

BUF

^$563

American Airlines

11/14/25

12:03pm

BUF

11h 2m

CLT

MIA

11/14/25

11:05pm

MDE

American Airlines

11/22/25

3:45pm

MDE

18h 53m

MIA

CLT

11/23/25

10:38am

BUF

^$631

American Airlines

11/14/25

8:12am

BUF

14h 53m

ORD

MIA

11/14/25

11:05pm

MDE

American Airlines

11/22/25

1:25am

MDE

21h 31m

MIA

11/22/25

10:56pm

BUF

^$713

American Airlines

11/14/25

12:03pm

BUF

11h 2m

CLT

MIA

11/14/25

11:05pm

MDE

American Airlines

11/22/25

1:25am

MDE

21h 31m

MIA

11/22/25

10:56pm

BUF

^$742

JetBlue

11/14/25

6:45am

BUF

7h 45m

FLL

11/14/25

2:30pm

MDE

JetBlue

11/22/25

2:25pm

MDE

26h 41m

FLL

11/23/25

5:06pm

BUF

^$900

LATAM Airlines Group

11/14/25

6:00am

BUF

20h 5m

ATL

BOG

11/15/25

2:05am

MDE

LATAM Airlines Group

11/22/25

6:10am

MDE

17h 45m

BOG

ATL

11/22/25

11:55pm

BUF

^$956

LATAM Airlines Group

11/14/25

6:00am

BUF

14h

ATL

BOG

11/14/25

8:00pm

MDE

LATAM Airlines Group

11/22/25

2:25pm

MDE

26h 41m

FLL

11/23/25

5:06pm

BUF

^$1045

LATAM Airlines Group

11/14/25

6:00am

BUF

17h 35m

ATL

BOG

11/14/25

11:35pm

MDE

LATAM Airlines Group

11/22/25

6:10am

MDE

17h 45m

BOG

ATL

11/22/25

11:55pm

BUF

^$1131

Top Deals on flights from Buffalo to Medellin

Buffalo, US (BUF) - Medellin, CO (MDE)

JetBlue

Aug 17

7:20am

BUF

6h 35m

FLL

Aug 17

1:55pm

MDE

as low as

^$227

Buffalo, US (BUF) - Medellin, CO (MDE)

American Airlines

Aug 17

6:15am

BUF

14h

CLT

MIA

Aug 17

8:15pm

MDE

as low as

^$255

Buffalo, US (BUF) - Medellin, CO (MDE)

JetBlue

Aug 17

9:45am

BUF

28h 10m

JFK

FLL

Aug 18

1:55pm

MDE

as low as

^$281

Buffalo, US (BUF) - Medellin, CO (MDE)

Sep 1

10:55am

BUF

11h 56m

ORD

PTY

Sep 1

10:51pm

MDE

as low as

^$282

Buffalo, US (BUF) - Medellin, CO (MDE)

Aug 17

9:45am

BUF

19h 50m

JFK

Aug 18

5:35am

MDE

as low as

^$323

Buffalo, US (BUF) - Medellin, CO (MDE)

Aug 17

6:00am

BUF

22h 42m

EWR

IAH

Aug 18

4:42am

MDE

as low as

^$333

Buffalo, US (BUF) - Medellin, CO (MDE)

Sep 1

8:00pm

BUF

16h 30m

IAD

SAL

Sep 2

12:30pm

MDE

as low as

^$393

Buffalo, US (BUF) - Medellin, CO (MDE)

Sep 1

6:00am

BUF

31h 42m

ATL

BOG

Sep 2

1:42pm

MDE

as low as

^$484

Buffalo, US (BUF) - Medellin, CO (MDE)

LATAM Airlines Group

Sep 1

12:02pm

BUF

10h 26m

ATL

BOG

Sep 1

10:28pm

MDE

as low as

^$517

Buffalo, US (BUF) - Medellin, CO (MDE)

Aug 17

10:30am

BUF

12h 21m

IAD

PTY

Aug 17

10:51pm

MDE

as low as

^$670

Buffalo, US (BUF) - Medellin, CO (MDE)

Aug 17

10:30am

BUF

11h 56m

IAD

BOG

Aug 17

10:26pm

MDE

as low as

^$1139

Frequently Asked Questions

Is there a direct flight from origin to destination?

There is no direct flight from Buffalo to Medellin. The available options are 1 stop and 2 stops flights provided by airlines such as JetBlue, American Airlines, and LATAM Airlines Group.

Are there convenient layover flights from Buffalo to Medellin?

Yes, there are convenient layover flights. Airlines offering options include JetBlue at $900 for a 1 stop, and $563 for a 2 stop flight; American Airlines at $631 for a 2 stop flight; and LATAM Airlines Group at $956 for a 2 stop flight.

What are the most convenient layover airports for the flight?

Consider layover airports such as New York John F Kennedy Airport, Fort Lauderdale Hollywood International Airport, Charlotte Douglas International Airport, Miami International Airport, and Hartsfield Jackson Atlanta International Airport for your trip.

What is the cheapest and fastest flight from Buffalo to Medellin?

The cheapest flight is with JetBlue for $563, taking 18 hours 30 minutes with 2 stops. The fastest flight is also with JetBlue for $900, taking 7 hours 45 minutes with 1 stop.

What are all possible destination arrival airports?

The possible destination arrival airport is Jose Maria Córdova International Airport in Medellin. Layover airports include New York John F Kennedy, Luis Munoz Marin, Charlotte Douglas, Miami International, Fort Lauderdale Hollywood, Hartsfield Jackson, and El Dorado.

What is the time difference between destination and arrival?

The time difference between Buffalo and Medellin is approximately 1 hour, with Medellin being 1 hour ahead of Buffalo.