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Flight Deals from Brussels to Detroit from $579

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Bundle + Save

Top flight deals from leading airlines:

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... and +100s more

Incredible Deals

Save up to 50% on select flights with Priceline

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Up to 1 stop
    $672
  • Up to 2 stops
    $614

Airlines

  • Aer Lingus
    $841
  • American Airlines
    $614
  • Austrian Airlines
    $7968
  • Brussels Airlines
    $672
  • Icelandair
    $768
  • JetBlue
    $2089
  • Lufthansa
    $678
  • SWISS
    $703
  • TAP Portugal
    $823
  • Turkish Airlines
    $866

Cabin Class

  • Economy
    $614

Departure Airports

  • Brussels Airport
    $614

Arrival Airports

  • Detroit Metropolitan Airport
    $614

Layover Airports

  • Chicago O Hare Airport
    $614
  • Dublin Airport
    $841
  • Frankfurt am Main Airport
    $678
  • General Edward Lawrence Logan International Airport
    $768
  • Humberto Delgado Airport (Lisbon Portela Airport)
    $823
  • Istanbul Airport
    $866
  • London Heathrow Airport
    $614
  • Montreal Trudeau Airport
    $672
  • New York John F Kennedy Airport
    $882
  • Newark Liberty Airport
    $7968
  • Reykjavik Keflavik Airport
    $768
  • Toronto Pearson Airport
    $761
  • Washington Dulles Airport
    $672
  • Zürich Airport
    $703

Best Price. GUARANTEED.

Exclusively for Priceline Members
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BUNDLE & SAVE

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On average save $240 per traveler
American Airlines Logo
American Airlines

09/18/25

BRU
27h 57m
LHR
ORD

09/19/25

DTW
American Airlines Logo
American Airlines

09/24/25

DTW
22h 47m
ORD
LHR

09/25/25

BRU
$614
Brussels Airlines Logo
Brussels Airlines

09/18/25

BRU
11h 29m
YUL

09/18/25

DTW
Brussels Airlines Logo
Brussels Airlines

09/24/25

DTW
16h 45m
IAD

09/25/25

BRU
$672
Lufthansa Logo
Lufthansa

09/18/25

BRU
7h 10m
FRA

09/18/25

DTW
Lufthansa Logo
Lufthansa

09/24/25

DTW
22h 10m
YUL

09/25/25

BRU
$678
Lufthansa Logo
Lufthansa

09/19/25

BRU
7h 10m
FRA

09/19/25

DTW
Lufthansa Logo
Lufthansa

09/27/25

DTW
18h 47m
ORD

09/28/25

BRU
$683
Lufthansa Logo
Lufthansa

09/18/25

BRU
7h 10m
FRA

09/18/25

DTW
Lufthansa Logo
Lufthansa

09/24/25

DTW
22h 35m
ORD
FRA

09/25/25

BRU
$690
Lufthansa Logo
Lufthansa

09/18/25

BRU
11h 52m
FRA
ORD

09/18/25

DTW
Lufthansa Logo
Lufthansa

09/24/25

DTW
22h 35m
ORD
FRA

09/25/25

BRU
$700
SWISS Logo
SWISS

09/18/25

BRU
15h 27m
ZRH
ORD

09/18/25

DTW
SWISS Logo
SWISS

09/24/25

DTW
16h 40m
ORD

09/25/25

BRU
$703
Brussels Airlines Logo
Brussels Airlines

09/18/25

BRU
5h 49m
YYZ

09/18/25

DTW
Brussels Airlines Logo
Brussels Airlines

09/24/25

DTW
23h 36m
ORD
FRA

09/25/25

BRU
$761
SWISS Logo
SWISS

09/18/25

BRU
15h 27m
ZRH
ORD

09/18/25

DTW
SWISS Logo
SWISS

09/24/25

DTW
20h 5m
ORD
ZRH

09/25/25

BRU
$762
Icelandair Logo
Icelandair

09/18/25

BRU
5h 30m
KEF

09/18/25

DTW
Icelandair Logo
Icelandair

09/24/25

DTW
28h 45m
BOS
KEF

09/25/25

BRU
$768
TAP Portugal Logo
TAP Portugal

09/18/25

BRU
28h 9m
LIS
BOS

09/19/25

DTW
TAP Portugal Logo
TAP Portugal

09/24/25

DTW
28h 15m
BOS
LIS

09/25/25

BRU
$823
Aer Lingus Logo
Aer Lingus

09/18/25

BRU
9h 44m
DUB
BOS

09/18/25

DTW
Aer Lingus Logo
Aer Lingus

09/24/25

DTW
26h 58m
BOS
DUB

09/25/25

BRU
$841
Turkish Airlines Logo
Turkish Airlines

09/18/25

BRU
24h 15m
IST

09/19/25

DTW
Turkish Airlines Logo
Turkish Airlines

09/24/25

DTW
24h 20m
IST

09/25/25

BRU
$866
Icelandair Logo
Icelandair

09/18/25

BRU
21h 40m
KEF
JFK

09/19/25

DTW
Icelandair Logo
Icelandair

09/24/25

DTW
28h 45m
BOS
KEF

09/25/25

BRU
$882
JetBlue Logo
JetBlue

09/18/25

BRU
13h 20m
DUB
JFK

09/18/25

DTW
JetBlue Logo
JetBlue

09/24/25

DTW
21h 24m
JFK
DUB

09/25/25

BRU
$2089
Austrian Airlines Logo
Austrian Airlines

09/18/25

BRU
9h
LHR
IAD

09/18/25

DTW
Austrian Airlines Logo
Austrian Airlines

09/24/25

DTW
20h 20m
EWR
LHR

09/25/25

BRU
$7968

Top Deals on flights from Brussels to Detroit

Brussels, BE (BRU) - Detroit, US (DTT)

Aer Lingus Logo
Aer Lingus

Sep 3

BRU
9h 44m
DUB
BOS

Sep 3

DTW

as low as

$579

Brussels, BE (BRU) - Detroit, US (DTT)

 Logo

Jun 20

BRU
11h 12m
MAD
JFK

Jun 20

DTW

as low as

$596

Brussels, BE (BRU) - Detroit, US (DTT)

TAP Portugal Logo
TAP Portugal

Sep 3

BRU
17h 12m
LIS
EWR

Sep 3

DTW

as low as

$627

Brussels, BE (BRU) - Detroit, US (DTT)

JetBlue Logo
JetBlue

Aug 28

BRU
25h 36m
LHR
BOS

Aug 29

DTW

as low as

$642

Brussels, BE (BRU) - Detroit, US (DTT)

 Logo

Sep 5

BRU
15h 50m
WAW
JFK

Sep 5

DTW

as low as

$756

Brussels, BE (BRU) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Sep 4

BRU
27h 57m
LHR
ORD

Sep 5

DTW

as low as

$778

Brussels, BE (BRU) - Detroit, US (DTT)

American Airlines Logo
American Airlines

Sep 5

BRU
27h 31m
LHR
CLT

Sep 6

DTW

as low as

$778

Brussels, BE (BRU) - Detroit, US (DTT)

Icelandair Logo
Icelandair

Sep 4

BRU
5h 30m
KEF

Sep 4

DTW

as low as

$794

Brussels, BE (BRU) - Detroit, US (DTT)

 Logo

Sep 4

BRU
27h 57m
LHR
ORD

Sep 5

DTW

as low as

$906

Brussels, BE (BRU) - Detroit, US (DTT)

 Logo

Sep 4

BRU
14h 47m
MAD
ORD

Sep 4

DTW

as low as

$911

Brussels, BE (BRU) - Detroit, US (DTT)

 Logo

Aug 29

BRU
26h 10m
MAD
ORD

Aug 30

DTW

as low as

$917

Brussels, BE (BRU) - Detroit, US (DTT)

 Logo

Jul 25

BRU
12h 7m
HEL
ORD

Jul 25

DTW

as low as

$1330

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