$489 Business Class Flight Deals from Detroit to Santo Domingo

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Stops

Up to 1 stop
$1214
Up to 2 stops
$1218

Airlines

American Airlines
$1214

Cabin Class

First
$1214
Business
$1218

Departure Airports

Detroit Metropolitan Airport
$1214

Arrival Airports

Las Américas International Airport
$1214

Layover Airports

Charlotte Douglas International Airport
$1218
Miami International Airport
$1214
Reagan Washington National Airport
$1218

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BUNDLE & SAVE

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On average save $240 per traveler

American Airlines

07/22/25

6:15am

DTW

12h 5m

MIA

07/22/25

6:20pm

SDQ

American Airlines

07/29/25

7:00am

SDQ

16h 15m

MIA

07/29/25

11:15pm

DTW

^$1214

American Airlines

07/22/25

6:15am

DTW

9h 5m

MIA

07/22/25

3:20pm

SDQ

American Airlines

07/29/25

7:00am

SDQ

16h 15m

MIA

07/29/25

11:15pm

DTW

^$1214

American Airlines

07/22/25

6:15am

DTW

7h 13m

MIA

07/22/25

1:28pm

SDQ

American Airlines

07/29/25

7:00am

SDQ

16h 15m

MIA

07/29/25

11:15pm

DTW

^$1214

American Airlines

07/22/25

9:39am

DTW

11h 16m

DCA

MIA

07/22/25

8:55pm

SDQ

American Airlines

07/29/25

7:00am

SDQ

16h 15m

MIA

07/29/25

11:15pm

DTW

^$1218

American Airlines

07/22/25

9:39am

DTW

8h 41m

DCA

MIA

07/22/25

6:20pm

SDQ

American Airlines

07/29/25

7:20pm

SDQ

15h 56m

MIA

CLT

07/30/25

11:16am

DTW

^$1218

American Airlines

07/22/25

6:02am

DTW

9h 18m

DCA

MIA

07/22/25

3:20pm

SDQ

American Airlines

07/29/25

7:00am

SDQ

16h 15m

MIA

07/29/25

11:15pm

DTW

^$1218

American Airlines

07/22/25

6:00am

DTW

9h 20m

CLT

MIA

07/22/25

3:20pm

SDQ

American Airlines

07/29/25

7:00am

SDQ

16h 15m

MIA

07/29/25

11:15pm

DTW

^$1218

American Airlines

07/22/25

7:15am

DTW

11h 5m

CLT

MIA

07/22/25

6:20pm

SDQ

American Airlines

07/29/25

7:20pm

SDQ

15h 56m

MIA

CLT

07/30/25

11:16am

DTW

^$1218

American Airlines

07/22/25

9:39am

DTW

8h 41m

DCA

MIA

07/22/25

6:20pm

SDQ

American Airlines

07/29/25

7:00am

SDQ

16h 15m

MIA

07/29/25

11:15pm

DTW

^$1218

American Airlines

07/22/25

6:02am

DTW

9h 18m

DCA

MIA

07/22/25

3:20pm

SDQ

American Airlines

07/29/25

7:20pm

SDQ

15h 56m

MIA

CLT

07/30/25

11:16am

DTW

^$1218

American Airlines

07/22/25

6:15am

DTW

9h 5m

MIA

07/22/25

3:20pm

SDQ

American Airlines

07/29/25

7:20pm

SDQ

15h 56m

MIA

CLT

07/30/25

11:16am

DTW

^$1218

American Airlines

07/22/25

9:39am

DTW

11h 16m

DCA

MIA

07/22/25

8:55pm

SDQ

American Airlines

07/29/25

7:20pm

SDQ

15h 56m

MIA

CLT

07/30/25

11:16am

DTW

^$1218

American Airlines

07/22/25

6:15am

DTW

9h 5m

MIA

07/22/25

3:20pm

SDQ

American Airlines

07/29/25

2:35pm

SDQ

8h 40m

MIA

07/29/25

11:15pm

DTW

^$1444

American Airlines

07/22/25

6:15am

DTW

7h 13m

MIA

07/22/25

1:28pm

SDQ

American Airlines

07/29/25

2:35pm

SDQ

8h 40m

MIA

07/29/25

11:15pm

DTW

^$1444

Top Deals on flights Business Class from Detroit to Santo Domingo

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:15am

DTW

12h 5m

MIA

Jul 24

6:20pm

SDQ

as low as

^$489

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

7:31pm

DTW

17h 57m

CLT

MIA

Jul 25

1:28pm

SDQ

as low as

^$489

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:15am

DTW

9h 5m

MIA

Jul 24

3:20pm

SDQ

as low as

^$580

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:02am

DTW

12h 18m

DCA

MIA

Jul 24

6:20pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:15am

DTW

14h 40m

MIA

Jul 24

8:55pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

9:39am

DTW

8h 41m

DCA

MIA

Jul 24

6:20pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:15am

DTW

7h 13m

MIA

Jul 24

1:28pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

5:20pm

DTW

20h 8m

DCA

MIA

Jul 25

1:28pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:00am

DTW

12h 20m

CLT

MIA

Jul 24

6:20pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

7:15am

DTW

11h 5m

CLT

MIA

Jul 24

6:20pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:02am

DTW

9h 18m

DCA

MIA

Jul 24

3:20pm

SDQ

as low as

^$735

Detroit, US (DTT) - Santo Domingo, DO (SDQ)

American Airlines

Jul 24

6:00am

DTW

9h 20m

CLT

MIA

Jul 24

3:20pm

SDQ

as low as

^$735

Frequently Asked Questions

What are the most convenient layover airports for my flight?

For your flight from Detroit to Santo Domingo, convenient layover airports include Miami International Airport, Charlotte Douglas International Airport, and other major hubs that may connect with American Airlines.

What is the cheapest and fastest flight from Detroit to Santo Domingo?

The cheapest and fastest flight is with American Airlines at $1214, 1 stop, with a flight time of 7 hours 13 minutes via Miami International Airport.

What are all possible destination arrival airports?

The possible destination arrival airport is Las Américas International Airport, with layovers at Miami International Airport and Charlotte Douglas International Airport.

What is the time difference between destination and arrival?

Flying from Detroit to Santo Domingo typically involves a time difference of one hour, with Santo Domingo being one hour ahead of Detroit.

Is there a direct flight from Detroit to Santo Domingo?

There is no direct flight from Detroit Metropolitan Airport to Las Américas International Airport. The available flights are 1 stop with American Airlines priced at $1214, and 2 stops also with American Airlines priced at $1218.

Are there convenient layover flights from Detroit to Santo Domingo?

Yes, there are convenient layover flights from Detroit to Santo Domingo. American Airlines offers a 1 stop flight for $1214 with layovers at Miami International Airport, and a 2 stop flight for $1218 with layovers at Charlotte Douglas and Miami International Airports.