$812 Business Class Flight Deals from Detroit to Panama City

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... and +100s more

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Stops

Up to 1 stop
$1690
Up to 2 stops
$1513

Airlines

American Airlines
$1513
COPA Airlines
$1690

Cabin Class

Business
$1513

Departure Airports

Detroit Metropolitan Airport
$1513

Arrival Airports

Tocumen International Airport
$1513

Layover Airports

Charlotte Douglas International Airport
$1513
Chicago O Hare Airport
$1513
Miami International Airport
$1513
Washington Dulles Airport
$1690

Best Price. GUARANTEED.

Exclusively for Priceline Members
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BUNDLE & SAVE

Book a flight & hotel together for extra savings.

On average save $240 per traveler

American Airlines

07/22/25

8:53pm

DTW

17h 1m

ORD

MIA

07/23/25

12:54pm

PTY

American Airlines

07/29/25

1:55pm

PTY

8h 20m

MIA

07/29/25

11:15pm

DTW

^$1513

American Airlines

07/22/25

11:36am

DTW

26h 18m

CLT

MIA

07/23/25

12:54pm

PTY

American Airlines

07/29/25

1:55pm

PTY

8h 20m

MIA

07/29/25

11:15pm

DTW

^$1513

American Airlines

07/22/25

5:12pm

DTW

20h 42m

ORD

MIA

07/23/25

12:54pm

PTY

American Airlines

07/29/25

1:55pm

PTY

8h 20m

MIA

07/29/25

11:15pm

DTW

^$1513

American Airlines

07/22/25

7:31pm

DTW

18h 23m

CLT

MIA

07/23/25

12:54pm

PTY

American Airlines

07/29/25

1:55pm

PTY

8h 20m

MIA

07/29/25

11:15pm

DTW

^$1513

American Airlines

07/22/25

3:03pm

DTW

22h 51m

CLT

MIA

07/23/25

12:54pm

PTY

American Airlines

07/29/25

1:55pm

PTY

8h 20m

MIA

07/29/25

11:15pm

DTW

^$1513

American Airlines

07/22/25

12:38pm

DTW

25h 16m

ORD

MIA

07/23/25

12:54pm

PTY

American Airlines

07/29/25

1:55pm

PTY

8h 20m

MIA

07/29/25

11:15pm

DTW

^$1542

COPA Airlines

07/22/25

7:48pm

DTW

11h 25m

IAD

07/23/25

6:13am

PTY

COPA Airlines

07/29/25

7:55am

PTY

13h 10m

ORD

07/29/25

10:05pm

DTW

^$1690

COPA Airlines

07/22/25

7:48pm

DTW

11h 45m

IAD

07/23/25

6:33am

PTY

COPA Airlines

07/29/25

7:55am

PTY

11h 50m

ORD

07/29/25

8:45pm

DTW

^$1690

COPA Airlines

07/22/25

7:48pm

DTW

11h 25m

IAD

07/23/25

6:13am

PTY

COPA Airlines

07/29/25

10:29pm

PTY

10h 44m

IAD

07/30/25

10:13am

DTW

^$1690

COPA Airlines

07/22/25

6:00am

DTW

8h 31m

IAD

07/22/25

1:31pm

PTY

COPA Airlines

07/29/25

7:30pm

PTY

13h 43m

IAD

07/30/25

10:13am

DTW

^$1690

COPA Airlines

07/22/25

7:48pm

DTW

11h 45m

IAD

07/23/25

6:33am

PTY

COPA Airlines

07/29/25

7:30pm

PTY

13h 43m

IAD

07/30/25

10:13am

DTW

^$1690

COPA Airlines

07/22/25

6:00am

DTW

8h 31m

IAD

07/22/25

1:31pm

PTY

COPA Airlines

07/29/25

7:55am

PTY

11h 50m

ORD

07/29/25

8:45pm

DTW

^$1690

COPA Airlines

07/22/25

6:00am

DTW

8h 31m

IAD

07/22/25

1:31pm

PTY

COPA Airlines

07/29/25

6:38pm

PTY

14h 35m

IAD

07/30/25

10:13am

DTW

^$1690

COPA Airlines

07/22/25

6:00am

DTW

8h 31m

IAD

07/22/25

1:31pm

PTY

COPA Airlines

07/29/25

10:29pm

PTY

10h 44m

IAD

07/30/25

10:13am

DTW

^$1690

COPA Airlines

07/22/25

6:00am

DTW

8h 31m

IAD

07/22/25

1:31pm

PTY

COPA Airlines

07/29/25

7:55am

PTY

13h 10m

ORD

07/29/25

10:05pm

DTW

^$1690

COPA Airlines

07/22/25

7:48pm

DTW

11h 25m

IAD

07/23/25

6:13am

PTY

COPA Airlines

07/29/25

7:55am

PTY

11h 50m

ORD

07/29/25

8:45pm

DTW

^$1690

COPA Airlines

07/22/25

7:48pm

DTW

11h 45m

IAD

07/23/25

6:33am

PTY

COPA Airlines

07/29/25

10:29pm

PTY

10h 44m

IAD

07/30/25

10:13am

DTW

^$1690

COPA Airlines

07/22/25

7:48pm

DTW

11h 45m

IAD

07/23/25

6:33am

PTY

COPA Airlines

07/29/25

7:55am

PTY

13h 10m

ORD

07/29/25

10:05pm

DTW

^$1690

Top Deals on flights Business Class from Detroit to Panama City

Detroit, US (DTT) - Panama City, PA (PTY)

COPA Airlines

Jul 24

8:50am

DTW

12h 45m

ORD

Jul 24

8:35pm

PTY

as low as

^$812

Detroit, US (DTT) - Panama City, PA (PTY)

COPA Airlines

Jul 24

6:00am

DTW

8h 31m

IAD

Jul 24

1:31pm

PTY

as low as

^$812

Detroit, US (DTT) - Panama City, PA (PTY)

COPA Airlines

Jul 24

10:32am

DTW

11h 3m

ORD

Jul 24

8:35pm

PTY

as low as

^$812

Detroit, US (DTT) - Panama City, PA (PTY)

COPA Airlines

Jul 24

7:48pm

DTW

11h 25m

IAD

Jul 25

6:13am

PTY

as low as

^$812

Detroit, US (DTT) - Panama City, PA (PTY)

American Airlines

Jul 24

6:15am

DTW

7h 39m

MIA

Jul 24

12:54pm

PTY

as low as

^$948

Detroit, US (DTT) - Panama City, PA (PTY)

COPA Airlines

Jul 24

10:32am

DTW

27h 50m

ORD

Jul 25

1:22pm

PTY

as low as

^$1441

Detroit, US (DTT) - Panama City, PA (PTY)

COPA Airlines

Jul 24

8:50am

DTW

29h 32m

ORD

Jul 25

1:22pm

PTY

as low as

^$1441

Frequently Asked Questions

Is there a direct flight from Detroit to Panama City?

There is no direct flight from Detroit to Panama City.

Are there convenient layover flights from Detroit to Panama City?

Yes, convenient layover flights from Detroit to Panama City include American Airlines for $1962 with a 1 stop at Miami, and COPA Airlines for $1690 with a 1 stop at Washington Dulles. A 2 stop option is also available with American Airlines for $1513.

What are the most convenient layover airports for my flight?

The most convenient layover airports for your flight are Miami International Airport, Washington Dulles Airport, Charlotte Douglas International Airport, George Bush Intercontinental Airport, and Orlando International Airport.

What is the cheapest and fastest flight from Detroit to Panama City?

The cheapest flight is $1513 with American Airlines (2 stops, 26 hours 18 minutes). The fastest flight is $1962 with American Airlines (1 stop, 7 hours 39 minutes).

What are all possible destination arrival airports?

The possible destination arrival airport for your flight is Tocumen International Airport in Panama City.

What is the time difference between destination and arrival?

The time difference between Detroit and Panama City is typically one hour, with Panama being one hour ahead of Detroit.

Flights to Panama City

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Top Destinations

Origins

Return flights

Cabin Class

Business Class Flights From Panama City To Detroit

➔ Flights From Detroit To Panama City

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Business Class Flight Deals from Detroit to Panama City from $812

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights Business Class from Detroit to Panama City

Frequently Asked Questions

Flights to Panama City