$209 Business Class Flight Deals from Buffalo to Chicago

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Stops

Nonstop
from $382
Up to 1 stop
$412

Airlines

American Airlines
$382

Cabin Class

First
$382

Departure Airports

Buffalo Niagara International Airport
$382

Arrival Airports

Chicago O Hare Airport
$382

Layover Airports

Charlotte Douglas International Airport
$412
New York LaGuardia Airport
$412
Reagan Washington National Airport
$412

Best Price. GUARANTEED.

Exclusively for Priceline Members
Tired of searching? Book now!
We'll refund the difference if you find a lower price.

BUNDLE & SAVE

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On average save $240 per traveler

American Airlines

07/29/25

8:02am

BUF

1h 54m

Direct

07/29/25

8:56am

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$382

American Airlines

07/29/25

5:05am

BUF

1h 52m

Direct

07/29/25

5:57am

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$382

American Airlines

07/29/25

12:26pm

BUF

1h 58m

Direct

07/29/25

1:24pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$392

American Airlines

07/29/25

5:30am

BUF

7h 20m

DCA

07/29/25

11:50am

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

1:47pm

BUF

4h 50m

CLT

07/29/25

5:37pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

2:52pm

BUF

4h 32m

DCA

07/29/25

6:24pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

6:00am

BUF

5h 59m

LGA

07/29/25

10:59am

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

5:47pm

BUF

6h 42m

DCA

07/29/25

11:29pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

5:30am

BUF

5h 52m

DCA

07/29/25

10:22am

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

6:00am

BUF

5h 9m

LGA

07/29/25

10:09am

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

6:28am

BUF

5h 9m

CLT

07/29/25

10:37am

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

10:00am

BUF

5h 15m

CLT

07/29/25

2:15pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

1:47pm

BUF

6h 29m

CLT

07/29/25

7:16pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$412

American Airlines

07/29/25

5:05am

BUF

1h 52m

Direct

07/29/25

5:57am

ORD

American Airlines

08/05/25

9:09am

ORD

1h 46m

Direct

08/05/25

11:55am

BUF

^$428

American Airlines

07/29/25

8:02am

BUF

1h 54m

Direct

07/29/25

8:56am

ORD

American Airlines

08/05/25

9:09am

ORD

1h 46m

Direct

08/05/25

11:55am

BUF

^$428

American Airlines

07/29/25

5:00pm

BUF

1h 55m

Direct

07/29/25

5:55pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$435

American Airlines

07/29/25

12:26pm

BUF

1h 58m

Direct

07/29/25

1:24pm

ORD

American Airlines

08/05/25

9:09am

ORD

1h 46m

Direct

08/05/25

11:55am

BUF

^$437

American Airlines

07/29/25

11:24am

BUF

7h 30m

LGA

07/29/25

5:54pm

ORD

American Airlines

08/05/25

7:25pm

ORD

1h 43m

Direct

08/05/25

10:08pm

BUF

^$442

American Airlines

07/29/25

8:02am

BUF

1h 54m

Direct

07/29/25

8:56am

ORD

American Airlines

08/05/25

8:05am

ORD

5h 17m

DCA

08/05/25

2:22pm

BUF

^$448

American Airlines

07/29/25

5:05am

BUF

1h 52m

Direct

07/29/25

5:57am

ORD

American Airlines

08/05/25

5:15am

ORD

6h 42m

CLT

08/05/25

12:57pm

BUF

^$448

American Airlines

07/29/25

8:02am

BUF

1h 54m

Direct

07/29/25

8:56am

ORD

American Airlines

08/05/25

7:05am

ORD

4h 52m

CLT

08/05/25

12:57pm

BUF

^$448

American Airlines

07/29/25

8:02am

BUF

1h 54m

Direct

07/29/25

8:56am

ORD

American Airlines

08/05/25

5:49pm

ORD

5h 10m

DCA

08/05/25

11:59pm

BUF

^$448

American Airlines

07/29/25

5:05am

BUF

1h 52m

Direct

07/29/25

5:57am

ORD

American Airlines

08/05/25

12:37pm

ORD

4h 57m

CLT

08/05/25

6:34pm

BUF

^$448

American Airlines

07/29/25

5:05am

BUF

1h 52m

Direct

07/29/25

5:57am

ORD

American Airlines

08/05/25

7:05am

ORD

4h 52m

CLT

08/05/25

12:57pm

BUF

^$448

American Airlines

07/29/25

8:02am

BUF

1h 54m

Direct

07/29/25

8:56am

ORD

American Airlines

08/05/25

12:37pm

ORD

4h 57m

CLT

08/05/25

6:34pm

BUF

^$448

American Airlines

07/29/25

5:05am

BUF

1h 52m

Direct

07/29/25

5:57am

ORD

American Airlines

08/05/25

5:49pm

ORD

5h 10m

DCA

08/05/25

11:59pm

BUF

^$448

American Airlines

07/29/25

5:05am

BUF

1h 52m

Direct

07/29/25

5:57am

ORD

American Airlines

08/05/25

8:05am

ORD

5h 17m

DCA

08/05/25

2:22pm

BUF

^$448

American Airlines

07/29/25

8:02am

BUF

1h 54m

Direct

07/29/25

8:56am

ORD

American Airlines

08/05/25

11:40am

ORD

4h 37m

DCA

08/05/25

5:17pm

BUF

^$448

American Airlines

07/29/25

6:00am

BUF

5h 59m

LGA

07/29/25

10:59am

ORD

American Airlines

08/05/25

9:09am

ORD

1h 46m

Direct

08/05/25

11:55am

BUF

^$457

American Airlines

07/29/25

6:00am

BUF

5h 9m

LGA

07/29/25

10:09am

ORD

American Airlines

08/05/25

9:09am

ORD

1h 46m

Direct

08/05/25

11:55am

BUF

^$457

Top Deals on flights Business Class from Buffalo to Chicago

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

5:05am

BUF

1h 52m

Direct

Jul 29

5:57am

ORD

as low as

^$209

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

8:02am

BUF

1h 54m

Direct

Jul 29

8:56am

ORD

as low as

^$209

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

12:26pm

BUF

1h 58m

Direct

Jul 29

1:24pm

ORD

as low as

^$235

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

2:52pm

BUF

4h 32m

DCA

Jul 29

6:24pm

ORD

as low as

^$239

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

1:47pm

BUF

4h 50m

CLT

Jul 29

5:37pm

ORD

as low as

^$239

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

5:30am

BUF

7h 20m

DCA

Jul 29

11:50am

ORD

as low as

^$239

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

6:28am

BUF

5h 9m

CLT

Jul 29

10:37am

ORD

as low as

^$239

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

10:00am

BUF

5h 15m

CLT

Jul 29

2:15pm

ORD

as low as

^$239

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

1:47pm

BUF

6h 29m

CLT

Jul 29

7:16pm

ORD

as low as

^$239

Buffalo, US (BUF) - Chicago, US (CHI)

American Airlines

Jul 29

5:00pm

BUF

1h 55m

Direct

Jul 29

5:55pm

ORD

as low as

^$280

Frequently Asked Questions

What is the time difference between destination and arrival?

There is a one-hour time difference between Buffalo and Chicago, with Chicago being an hour behind.

Is there a direct flight from Buffalo to Chicago?

Yes, there is a direct flight from Buffalo to Chicago. American Airlines offers a non-stop flight priced at $382, with a flight time of 1 hour and 52 minutes.

Are there convenient layover flights from Buffalo to Chicago?

Yes, there is a convenient 1 stop flight from Buffalo Niagara International Airport to Chicago O Hare Airport with American Airlines at a price of $412, with a layover at Reagan Washington National Airport and a flight time of 4 hours 32 minutes.

What are the most convenient layover airports for my flight?

For your flight from Buffalo to Chicago, convenient layover airports include Reagan Washington National Airport, O'Hare International Airport, Detroit Metropolitan Wayne County Airport, Philadelphia International Airport, and Charlotte Douglas International Airport.

What is the cheapest and fastest flight from Buffalo to Chicago?

The cheapest direct flight is with American Airlines at $382, taking 1 hour 52 minutes. No faster options are available.

What are all possible destination arrival airports?

The possible destination arrival airport is Chicago O'Hare Airport.

Flights to Chicago

Top Destinations

Origins

Return flights

Cabin Class

➔ Business Class Flights From Chicago To Buffalo

➔ Flights From Buffalo To Chicago

Business Class Flight Deals from Buffalo to Chicago from $209

Stops

Airlines

Cabin Class

Departure Airports

Arrival Airports

Layover Airports

Best Price. GUARANTEED.

Top Deals on flights Business Class from Buffalo to Chicago

Frequently Asked Questions

Flights to Chicago