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Flight Deals from Brussels to Istanbul from $92

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Save an average of $240 per person when bundling your flight and hotel together with Priceline

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Stops

  • Nonstop
    from $328
  • Up to 1 stop
    $395
  • Up to 2 stops
    $625

Airlines

  • Aegean Airlines
    $429
  • Air Malta
    $510
  • Air SERBIA a.d. Beograd
    $408
  • Brussels Airlines
    $539
  • ITA Airways
    $604
  • KLM
    $406
  • LOT Polish Airlines
    $395
  • Lufthansa
    $538
  • Pegasus Airlines
    $328
  • Sky Express
    $472
  • TAROM
    $432
  • Turkish Airlines
    $381

Cabin Class

  • Economy
    $328

Departure Airports

  • Brussels Airport
    $381
  • Brussels South Charleroi Airport
    $328

Arrival Airports

  • Istanbul Airport
    $381
  • Sabiha Gökçen International Airport
    $328

Layover Airports

  • Amsterdam Airport Schiphol
    $406
  • Antalya International Airport
    $437
  • Belgrade Nikola Tesla Airport
    $408
  • Bucharest Otopeni Airport
    $432
  • Budapest Liszt Ferenc International Airport
    $541
  • Eleftherios Venizelos International Airport
    $429
  • Frankfurt am Main Airport
    $538
  • Malta International Airport
    $510
  • Munich Airport
    $661
  • Paris Charles de Gaulle Airport
    $425
  • Rome Fiumicino Airport
    $604
  • Thessaloniki Macedonia International Airport
    $625
  • Warsaw Chopin Airport
    $395

Best Price. GUARANTEED.

Exclusively for Priceline Members
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BUNDLE & SAVE

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On average save $240 per traveler
Pegasus Airlines Logo
Pegasus Airlines

07/01/25

CRL
4h 20m
Direct

07/01/25

SAW
Pegasus Airlines Logo
Pegasus Airlines

07/14/25

SAW
2h 35m
Direct

07/14/25

CRL
$328
Pegasus Airlines Logo
Pegasus Airlines

06/30/25

CRL
4h 20m
Direct

06/30/25

SAW
Pegasus Airlines Logo
Pegasus Airlines

07/14/25

SAW
2h 35m
Direct

07/14/25

CRL
$328
Turkish Airlines Logo
Turkish Airlines

06/30/25

BRU
4h 30m
Direct

06/30/25

IST
Turkish Airlines Logo
Turkish Airlines

07/09/25

IST
2h 30m
Direct

07/09/25

BRU
$381
Turkish Airlines Logo
Turkish Airlines

06/29/25

BRU
4h 30m
Direct

06/29/25

IST
Turkish Airlines Logo
Turkish Airlines

07/07/25

IST
2h 30m
Direct

07/07/25

BRU
$386
LOT Polish Airlines Logo
LOT Polish Airlines

07/01/25

BRU
13h 35m
WAW

07/01/25

IST
LOT Polish Airlines Logo
LOT Polish Airlines

07/22/25

IST
25h 10m
WAW

07/23/25

BRU
$395
LOT Polish Airlines Logo
LOT Polish Airlines

07/08/25

BRU
17h 30m
WAW

07/09/25

IST
LOT Polish Airlines Logo
LOT Polish Airlines

07/16/25

IST
4h 55m
WAW

07/16/25

BRU
$397
KLM Logo
KLM

06/30/25

BRU
14h 55m
AMS

06/30/25

SAW
KLM Logo
KLM

07/18/25

SAW
16h 45m
AMS

07/19/25

BRU
$406
Air SERBIA a.d. Beograd Logo
Air SERBIA a.d. Beograd

06/30/25

BRU
18h 35m
BEG

07/01/25

IST
Air SERBIA a.d. Beograd Logo
Air SERBIA a.d. Beograd

07/16/25

IST
4h 45m
BEG

07/16/25

BRU
$408
KLM Logo
KLM

07/06/25

BRU
26h
AMS

07/07/25

SAW
KLM Logo
KLM

07/12/25

SAW
11h 13m
CDG

07/12/25

BRU
$425
Aegean Airlines Logo
Aegean Airlines

06/30/25

BRU
13h 50m
ATH

07/01/25

IST
Aegean Airlines Logo
Aegean Airlines

07/07/25

IST
6h 45m
ATH

07/07/25

BRU
$429
TAROM Logo
TAROM

07/11/25

BRU
14h 55m
OTP

07/12/25

IST
TAROM Logo
TAROM

07/16/25

IST
8h 10m
OTP

07/16/25

BRU
$432
Pegasus Airlines Logo
Pegasus Airlines

07/01/25

CRL
4h 20m
Direct

07/01/25

SAW
Pegasus Airlines Logo
Pegasus Airlines

07/06/25

SAW
6h 25m
AYT

07/06/25

CRL
$437
Air SERBIA a.d. Beograd Logo
Air SERBIA a.d. Beograd

07/09/25

BRU
18h 35m
BEG

07/10/25

IST
Air SERBIA a.d. Beograd Logo
Air SERBIA a.d. Beograd

07/11/25

IST
4h 45m
BEG

07/11/25

BRU
$441
TAROM Logo
TAROM

07/09/25

BRU
14h 5m
OTP

07/10/25

IST
TAROM Logo
TAROM

07/16/25

IST
8h 10m
OTP

07/16/25

BRU
$450
Aegean Airlines Logo
Aegean Airlines

07/28/25

BRU
13h 50m
ATH

07/29/25

IST
Aegean Airlines Logo
Aegean Airlines

08/04/25

IST
13h 30m
ATH

08/05/25

BRU
$452
Pegasus Airlines Logo
Pegasus Airlines

06/30/25

CRL
4h 20m
Direct

06/30/25

SAW
Pegasus Airlines Logo
Pegasus Airlines

07/06/25

SAW
6h 25m
AYT

07/06/25

CRL
$466
Sky Express Logo
Sky Express

06/29/25

BRU
12h 10m
ATH

06/30/25

IST
Sky Express Logo
Sky Express

07/13/25

IST
15h 20m
ATH

07/14/25

BRU
$472
Air Malta Logo
Air Malta

06/30/25

BRU
13h 30m
MLA

07/01/25

IST
Air Malta Logo
Air Malta

07/07/25

IST
8h 40m
MLA

07/07/25

BRU
$510
Sky Express Logo
Sky Express

07/23/25

BRU
18h 25m
ATH

07/24/25

IST
Sky Express Logo
Sky Express

07/27/25

IST
15h 20m
ATH

07/28/25

BRU
$516
Air Malta Logo
Air Malta

07/07/25

BRU
13h 30m
MLA

07/08/25

IST
Air Malta Logo
Air Malta

07/10/25

IST
22h 5m
MLA

07/11/25

BRU
$518
Lufthansa Logo
Lufthansa

06/30/25

BRU
6h 55m
FRA

06/30/25

IST
Lufthansa Logo
Lufthansa

07/07/25

IST
6h 40m
FRA

07/07/25

BRU
$538
Lufthansa Logo
Lufthansa

07/02/25

BRU
8h 30m
FRA

07/02/25

IST
Lufthansa Logo
Lufthansa

07/09/25

IST
4h 40m
FRA

07/09/25

BRU
$538
Brussels Airlines Logo
Brussels Airlines

07/16/25

BRU
18h 50m
ATH

07/17/25

IST
Brussels Airlines Logo
Brussels Airlines

07/24/25

IST
13h 50m
FRA

07/25/25

BRU
$539
Brussels Airlines Logo
Brussels Airlines

07/15/25

BRU
15h 10m
BUD

07/16/25

IST
Brussels Airlines Logo
Brussels Airlines

07/24/25

IST
13h 50m
FRA

07/25/25

BRU
$541
Brussels Airlines Logo
Brussels Airlines

07/22/25

BRU
15h 10m
BUD

07/23/25

IST
Brussels Airlines Logo
Brussels Airlines

07/28/25

IST
5h 45m
ATH

07/28/25

BRU
$596
ITA Airways Logo
ITA Airways

07/10/25

BRU
19h 40m
FCO

07/11/25

IST
ITA Airways Logo
ITA Airways

07/15/25

IST
18h
FCO

07/16/25

BRU
$604
KLM Logo
KLM

07/29/25

BRU
7h 55m
AMS

07/29/25

SAW
KLM Logo
KLM

08/05/25

SAW
11h 13m
CDG

08/05/25

BRU
$604
Aegean Airlines Logo
Aegean Airlines

06/29/25

BRU
19h
ATH

06/30/25

IST
Aegean Airlines Logo
Aegean Airlines

07/06/25

IST
18h 45m
ATH
SKG

07/07/25

BRU
$625
Lufthansa Logo
Lufthansa

06/29/25

BRU
14h 35m
MUC
FRA

06/29/25

IST
Lufthansa Logo
Lufthansa

07/06/25

IST
13h 50m
FRA

07/07/25

BRU
$661
ITA Airways Logo
ITA Airways

07/11/25

BRU
15h 50m
FCO

07/12/25

IST
ITA Airways Logo
ITA Airways

07/15/25

IST
12h 50m
FCO

07/16/25

BRU
$667

Top Deals on flights from Brussels to Istanbul

Brussels, BE (BRU) - Istanbul, TR (IST)

Pegasus Airlines Logo
Pegasus Airlines

Aug 27

CRL
4h 20m
Direct

Aug 27

SAW

as low as

$92

Brussels, BE (BRU) - Istanbul, TR (IST)

Sky Express Logo
Sky Express

Nov 9

BRU
19h 25m
ATH

Nov 10

IST

as low as

$115

Brussels, BE (BRU) - Istanbul, TR (IST)

KLM Logo
KLM

Oct 1

BRU
10h 10m
AMS

Oct 1

IST

as low as

$167

Brussels, BE (BRU) - Istanbul, TR (IST)

Air SERBIA a.d. Beograd Logo
Air SERBIA a.d. Beograd

Sep 19

BRU
17h 40m
BEG

Sep 20

IST

as low as

$173

Brussels, BE (BRU) - Istanbul, TR (IST)

Aegean Airlines Logo
Aegean Airlines

Nov 1

BRU
14h 55m
ATH

Nov 2

IST

as low as

$174

Brussels, BE (BRU) - Istanbul, TR (IST)

Turkish Airlines Logo
Turkish Airlines

Nov 4

BRU
5h 30m
Direct

Nov 4

IST

as low as

$191

Brussels, BE (BRU) - Istanbul, TR (IST)

TAROM Logo
TAROM

Nov 9

BRU
15h 30m
OTP

Nov 10

IST

as low as

$196

Brussels, BE (BRU) - Istanbul, TR (IST)

LOT Polish Airlines Logo
LOT Polish Airlines

Sep 27

BRU
18h 40m
WAW

Sep 28

IST

as low as

$207

Brussels, BE (BRU) - Istanbul, TR (IST)

Air Malta Logo
Air Malta

Jun 16

BRU
13h 30m
MLA

Jun 17

IST

as low as

$219

Brussels, BE (BRU) - Istanbul, TR (IST)

Air Europa Logo
Air Europa

Nov 11

BRU
20h
MAD

Nov 12

IST

as low as

$224

Brussels, BE (BRU) - Istanbul, TR (IST)

Aegean Airlines Logo
Aegean Airlines

Sep 10

BRU
25h 30m
ATH
HER

Sep 11

IST

as low as

$229

Brussels, BE (BRU) - Istanbul, TR (IST)

Tunisair Logo
Tunisair

Nov 25

BRU
15h 20m
TUN

Nov 26

IST

as low as

$249

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